Orotidine Monophosphate Decarboxylase: A Mechanistic Dialogue

E-Book Overview

K.N. Houk, D.J. Tantillo, C. Stanton, Y. Hu: What Has Theory and Crystallography Revealed About the Mechanism of Catalysis by Orotidine Monophosphate Decarboxylase? .-

N. Wu, E.F. Pai: Crystallographic Studies of Native and Mutant Orotidine 5’Phosphate Decarboxylases .-

B.G. Miller: Insight into the Catalytic Mechanism of Orotidine 5’Phosphate Decarboxylase from Crystallography and Mutagenesis .-

J.A. Smiley: Survey of Enzymological Data on ODCase .-

M. Lundberg, M.R.A. Blomberg, P.E. Siegbahn: Developing Active Site Models of ODCase - from Large Quantum Models to QM/MM Approach .-

J. Gao, K.L.Byun, R. Kluger: Catalysis by Enzyme Confromational Change


E-Book Content

238 Topics in Current Chemistry Editorial Board: A. de Meijere · K.N. Houk · H. Kessler · J.-M. Lehn · S.V. Ley S.L. Schreiber · J. Thiem · B.M. Trost · F. Vgtle · H. Yamamoto Topics in Current Chemistry Recently Published and Forthcoming Volumes Natural Product Synthesis II Volume Editor: Mulzer, J.H. Vol. 244, 2004 Natural Product Synthesis I Volume Editor: Mulzer, J.H. Vol. 243, 2004 Immobilized Catalysts Volume Editor: Kirschning, A. Vol. 242, 2004 Transition Metal and Rare Earth Compounds III Volume Editor: Yersin, H. Vol. 241, 2004 The Chemistry of Pheromones and Other Semiochemicals II Volume Editor: Schulz, S. Vol. 240, 2004 The Chemistry of Pheromones and Other Semiochemicals I Volume Editor: Schulz, S. Vol. 239, 2004 Orotidine Monophosphate Decarboxylase Volume Editors: Lee, J.K., Tantillo, D.J. Vol. 238, 2004 Long-Range Charge Transfer in DNA II Volume Editor: Schuster, G.B. Vol. 237, 2004 Long-Range Charge Transfer in DNA I Volume Editor: Schuster, G.B. Vol. 236, 2004 Spin Crossover in Transition Metal Compounds III Volume Editors: Gtlich, P., Goodwin, H.A. Vol. 235, 2004 Spin Crossover in Transition Metal Compounds II Volume Editors: Gtlich, P., Goodwin, H.A. Vol. 234, 2004 Spin Crossover in Transition Metal Compounds I Volume Editors: Gtlich, P., Goodwin, H.A. Vol. 233, 2004 New Aspects in Phosphorus Chemistry IV Volume Editor: Majoral, J.-P. Vol. 232, 2004 Elemental Sulfur and Sulfur-Rich Compounds II Volume Editor: Steudel, R. Vol. 231, 2003 Elemental Sulfur and Sulfur-Rich Compounds I Volume Editor: Steudel, R. Vol. 230, 2003 New Aspects in Phosphorus Chemistry III Volume Editor: Majoral, J.-P. Vol. 229, 2003 Dendrimers V Volume Editors: Schalley, C.A., Vgtle, F. Vol. 228, 2003 Colloid Chemistry II Volume Editor: Antonietti, M. Vol. 227, 2003 Colloid Chemistry I Volume Editor: Antonietti, M. Vol. 226, 2003 Modern Mass Spectrometry Volume Editor: Schalley, C.A. Vol. 225, 2003 Hypervalent Iodine Chemistry Volume Editor: Wirth, T. Vol. 224, 2003 Orotidine Monophosphate Decarboxylase A Mechanistic Dialogue Volume Editors: J.K. Lee, D.J. Tantillo With contributions by M.R.A. Blomberg · K.L. Byun · J. Gao · K.N. Houk · Y. Hu R. Kluger · M. Lundberg · B.G. Miller · E.F. Pai · P.E.M. Siegbahn J.A. Smiley · C. Stanton · D.J. Tantillo · N. Wu BD The series Topics in Current Chemistry presents critical reviews of the present and future trends in modern chemical research. The scope of coverage includes all areas of chemical science including the interfaces with related disciplines such as biology, medicine and materials science. The goal of each thematic volume is to give the non specialist reader, whether at the university or in industry, a comprehensive overview of an area where new insights are emerging that are of interest to a larger scientific audience. As a rule, contributions are specially commissioned. The editors and publishers will, however, always be pleased to receive suggestions and supplementary information. Papers are accepted for Topics in Current Chemistry in English. In references Topics in Current Chemistry is abbreviated Top
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