Natural Product Isolation (methods In Biotechnology)

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Glaxo Wellcome Research & Development, Herts, UK. Gives practical guidance in the process of extraction and isolation of natural products. Modifiedoutline format. Halftone graphs and illustrations. For researchers and scientists.

E-Book Content

  Natural Products Isolation METHODS IN BIOTECHNOLOGY” John M. Walker,SERIES EDITOR 7. Affinity Biosensors:TechniquesandProtocols,editedby Kim R. Rogers and Ashok Mulchandanl, 1998 6. Enzymeand Microbial Biosensors:Techniquesand Protocols,editedby Ashok Mulchandani and Kim R. Rogers, 1998 5. Biopesticides:Use andDelivery,editedby Franklin R. Hall and Julius J. Menn, 1998 4. Natural ProductsIsolation,editedby Richard J. I? Cannell, 1998 3. RecombinantProteinsfrom Plants:ProductionandIsolation of Clinically Useful Compounds,editedby Charles Cunningham and AndrewJ. R Portev, 1998 2. Protocolsin Bioremediation,editedby David Sheehan, 1997 1. Immobilizationof Enzymesand Cells,edltedby Gordon F: Bickerstafi 1997 Natural Products Isolation Edited by Richard J. P. Cannell Glaxo Wellcome Research & Development, Humana Press Stevenage, Herb, UK Totowa, New Jersey 0 1998 Humana Press lnc 999 Rtvervtew Drive, Suite 208 Totowa, New Jersey 075 12 All rights reserved No part of this book may be reproduced, stored m a retrieval system, or transmuted m any form or by any means, electronic, mechanical, photocopymg, mtcrofilmmg, recording, or otherwise without wrttten permtsston from the Pubhsher. Methods m Btotechnologyr” ISa trademark of The Humana Press lnc All authored papers, comments, opuuons, conclustons, or recommendattons are those of the author(s), and do not necessarily reflect the views of the publisher This pubhcatlon IS printed on acid-free paper @ ANSI 239 48-1984 (American Standards lnstttute) Permanence of Paper for Printed Library Materials Cover design by Patrtcta F Cleary For addmonal copies, prtcmg for bulk purchases, and/or mformatton about other Humana titles, contact Humana at the above address or at any of the followmg numbers. Tel 973-256-1699, Fax 973-256-8341, E-mall [email protected] corn, or vtstt our Webstte at www humanapress corn Photocopy Authorization Policy: Authorizatron to photocopy items for internal or personal use, or the Internal or personal use of specttic chents, 1sgranted by Humana Press lnc , provided that the base fee of US $8 00 per copy, plus US $00 25 per page, is paid directly to the Copyright Clearance Center at 222 Rosewood Drive, Danvers, MA 01923 For those organizations that have been granted a photocopy license from the CCC, a separate system of payment has been arranged and ISacceptable to Humana Press Inc. The fee code for users of the Transactional Reporting Service IS [O-89603-362-7/98 $8 00 + $00 251 Prmted m the United States of America 10 9 8 7 6 5 4 3 2 Library of Congress Cataloging m Pubhcatton Data Mam entry under title Methods m molecular btologyTM Natural products tsolatton/edlted by Richard J P Cannell. p. cm -(Methods m brotechnology, 4) Includes index ISBN o-89603-362-7 (alk paper) I. Natural products 2 Extraction (Chemtstry) I Cannell, Richard J P btotechnology (Totowa, NJ), 4 QD415 N355 1998 547 7-dc21 II Series Methods m 98-16651 CIP Preface Biodiversity 1sa term commonly used to denote the variety of species and the multiplicity of forms of life. But this variety is deeper than is generally imagined. In addition to the processesof primary metabolism that involve essentially the same chemistry across great swathes of life, there are a myriad of secondary metabolites-natural products-usually confined to a particular group of organisms, or to a single spec
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