Cardiovascular Benefits Of Omega-3 Polyunsaturated Fatty Acids: Volume 7 Solvay Pharmaceuticals Conferences

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During the last decades progress has been made in the treatment of patients who survived myocardial infarction. Nevertheless, patients who survive an acute myocardial infarction are at high risk, with life expectancy half that of their peers who have not experienced similar events, and with increased risk for subsequent cardiovascular events and death. The risk of sudden death increases with severity of systolic dysfunction after myocardial infarction. In recent years, it has become clear that in addition to risk factors such as overweight, lack of exercise, smoking, hypertension and hypercholesterolemia, psychosocial factors play a key role for prognosis in patients with myocardial infarction. Therefore, there is high medical need for drugs which lower the incidence of sudden death and have an effect on other risk factors such as depression. OMACOR?‚?®, a pharmaceutical preparation of highly purified and concentrated Omega-3 polyunsaturated acids, may present such a drug. It lowers the incidence of sudden death in patients with myocardial infarction and decreases depression. This publication focuses on the effect of Omega-3 polyunsaturated fatty acids on different risk factors in patients with cardiovascular disease. In addition, aspects of prevention of cardiovascular disease, risk factors and pharmacokinetics of Omega-3 fatty acids ethyl esters are considered.IOS Press is an international science, technical and medical publisher of high-quality books for academics, scientists, and professionals in all fields. Some of the areas we publish in: -Biomedicine -Oncology -Artificial intelligence -Databases and information systems -Maritime engineering -Nanotechnology -Geoengineering -All aspects of physics -E-governance -E-commerce -The knowledge economy -Urban studies -Arms control -Understanding and responding to terrorism -Medical informatics -Computer Sciences

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CARDIOVASCULAR BENEFITS OF OMEGA-3 POLYUNSATURATED FATTY ACIDS Solvay Pharmaceuticals Conferences Series Editors Werner Cautreels, Claus Steinborn and Lechoslaw Turski Volume 7 Previously published in this series Vol. 6 Vol. 5 Vol. 4 Vol. 3 Vol. 2 Vol. 1 B. Testa and L. Turski (Eds.), Virtual ADMET Assessment in Target Selection and Maturation C.G. Kruse, H.Y. Meltzer, C. Sennef and S.V. van de Witte (Eds.), Thinking About Cognition: Concepts, Targets and Therapeutics J. Antel, N. Finer, D. Heal and G. Krause (Eds.), Obesity and Metabolic Disorders G. Krause, J.R. Malagelada and U. Preuschoff (Eds.), Functional Disorders of the Gastrointestinal Tract J.G. Papp, M. Straub and D. Ziegler (Eds.), Atrial Fibrillation: New Therapeutic Concepts E. Ronken and G.J.M. van Scharrenburg (Eds.), Parkinson’s Disease ISSN 1566-7685 Cardiovascular Benefits of Omega-3 Polyunsaturated Fatty Acids Edited by B. Maisch Philipps University of Marburg, Marburg, Germany and R. Oelze Solvay Pharmaceuticals, Hannover, Germany Amsterdam • Berlin • Oxford • Tokyo • Washington, DC © 2006 The authors. All rights reserved. No part of this book may be reproduced, stored in a retrieval system, or transmitted, in any form or by any means, without prior written permission from the publisher. ISBN 978-1-58603-707-9 Library of Congress Control Number: 2006939183 Publisher IOS Press Nieuwe Hemweg 6B 1013 BG Amsterdam Netherlands fax: +31 20 687 0019 e-mail: [email protected] Distributor in the UK and Ireland Gazelle Books Services Ltd. White Cross Mills Hightown Lancaster LA1 4XS United Kingdom fax: +44 1524 63232 e-mail: [email protected] D
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