Good Clinical Practice In Assisted Reproduction

Good Clinical Practice in Assisted Reproduction This practical, user-friendly book comprehensively covers all aspects of the investigation and treatment of infertility, from clinical assessment of the male and female to the latest assisted technology. Chapters deal with IVF, intracytoplasmic sperm injection (ICSI), techniques of sperm retrieval and clinical aspects of pre-implantation genetic diagnosis (PGD). Guidance is given on how to set up and run a successful IVF programme. With its clinical focus, this book will be invaluable to doctors, embryologists and nurses working in the field of reproductive medicine, whether they are established specialists or in training. Good Clinical Practice in Assisted Reproduction Edited by Paul Serhal University College London Hospitals and Caroline Overton St. Michael’s Hospital and the Bristol Royal Infirmary published by the press syndicate of the university of cambridge The Pitt Building, Trumpington Street, Cambridge, United Kingdom cambridge university press The Edinburgh Building, Cambridge CB2 2RU, UK 40 West 20th Street, New York, NY 10011–4211, USA 477 Williamstown Road, Port Melbourne, VIC 3207, Australia ´ 13, 28014 Madrid, Spain Ruiz de Alarcon Dock House, The Waterfront, Cape Town 8001, South Africa http://www.cambridge.org
C Cambridge University Press 2004 This book is in copyright. Subject to statutory exception and to the provisions of relevant collective licensing agreements, no reproduction of any part may take place without the written permission of Cambridge University Press. First published 2004 Printed in the United Kingdom at the University Press, Cambridge Typefaces Minion 10.5/14 pt., Formata and Formata BQ System LATEX 2ε [tb] A catalogue record for this book is available from the British Library Library of Congress Cataloguing in Publication data Good clinical practice in assisted reproduction/edited by Paul Serhal, Caroline Overton. p. cm. Includes bibliographical references and index. ISBN 0 521 00091 2 (paperback) 1. Human reproductive technology. 2. Infertility – Treatment. I. Serhal, Paul, 1954– II. Overton, Caroline. [DNLM: 1. Reproductive Techniques, Assisted WQ 208 G646 2003] RC889.G655 2003 616.6 9206 – dc21 2003044039 ISBN 0 521 00091 2 paperback Every effort has been made in preparing this book to provide accurate and up-to-date information that is in accord with accepted standards and practice at the time of publication. Nevertheless, the authors, editors and publisher can make no warranties that the information contained herein is totally free from error, not least because clinical standards are constantly changing through research and regulation. The authors, editors and publisher therefore disclaim all liability for direct or consequential damages resulting from the use of material contained in this book. Readers are strongly advised to pay careful attention to information provided by the manufacturer of any drugs or equipment that they plan to use. Contents List of contributors Foreword by Bob Edwards Preface 1 Clinical assessment of the woman for assisted conception page vii xi xv 1 Domenico Massimo Ranieri 2 Clinical assessment and management of the infertile man 19 Suks Minhas and David