E-Book Overview
For more than four decades, scientists and researchers have relied on the Advances in Chromatography series for the most up-to-date information on a wide range of developments in chromatographic methods and applications. Volume 45 of this authoritative series once again compiles the work of expert contributors in order to present timely and cutting-edge reviews on a variety of related topics.This volume focuses on applying various chromatographic techniques to combinatorial methods and high-throughput analyses. The authors address various limitations to traditional techniques and present developments that enable scientists to analyze a higher volume of smaller molecules under high-throughput conditions more efficiently. Other practical topics include discussions of selection criteria for using alternative solvents and reagents, minimum requirements for utilizing readily available instrumentation and methods for new applications, the use of high-throughput purification for obtaining higher quality leads, and new chromatographic data on organic endocrine disrupters. Advances in Chromatography: Volume 45 provides a good starting point to gain quick and up-to-date knowledge of the field and its most recent developments. Each author's clear presentation of topics and vivid illustrations make the material accessible and engaging to a variety of chemists with different levels of technical skill.
E-Book Content
DK4478_C000.fm Page i Friday, September 22, 2006 8:48 AM Half Title Page VOLUME 45 Advances in CHROMATOGRAPHY DK4478_C000.fm Page ii Friday, September 22, 2006 8:48 AM DK4478_C000.fm Page iii Friday, September 22, 2006 8:48 AM Title Page VOLUME 45 Advances in CHROMATOGRAPHY EDITORS: ELI GRUSHK A Hebrew University of Jerusalem Jerusalem, Israel NELU GRINBERG Boehringer-Ingelheim Pharmaceutical, Inc. Ridgefield, Connecticut, U.S.A. Boca Raton London New York CRC Press is an imprint of the Taylor & Francis Group, an informa business DK4478_C000.fm Page iv Friday, September 22, 2006 8:48 AM CRC Press Taylor & Francis Group 6000 Broken Sound Parkway NW, Suite 300 Boca Raton, FL 33487-2742 © 2007 by Taylor & Francis Group, LLC CRC Press is an imprint of Taylor & Francis Group, an Informa business No claim to original U.S. Government works Printed in the United States of America on acid-free paper 10 9 8 7 6 5 4 3 2 1 International Standard Book Number-10: 1-57444-735-1 (Hardcover) International Standard Book Number-13: 978-1-57444-735-4 (Hardcover) This book contains information obtained from authentic and highly regarded sources. Reprinted material is quoted with permission, and sources are indicated. A wide variety of references are listed. Reasonable efforts have been made to publish reliable data and information, but the author and the publisher cannot assume responsibility for the validity of all materials or for the consequences of their use. No part of this book may be reprinted, reproduced, transmitted, or utilized in any form by any electronic, mechanical, or other means, now known or hereafter invented, including photocopying, microfilming, and recording, or in any information storage or retrieval system, without written permission from the publishers. For permission to photocopy or use material electronically from this work, please access www. copyright.com (http://www.copyright.com/) or contact the Copyright Clearance Center, Inc. (CCC) 222 Rosewood Drive, Danvers, MA 01923, 978-750-8400. CCC is a not-for-profit organization that provides licenses and registration for a variety of users. For organizations that have been granted a photocopy license by the CCC, a separate system of payment has been arranged. Trademark Notice: Product or corporate names may be trademarks or registered trademarks, and are used only for identi