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Although bone allografts were first utilized by McEwen in orthopaedic surgery in 1881, progress since then has been sporadic. With the growth of tissue banks and the greater availability of safe and sterile bone grafts, the pace has now quickened; in 2004, more than one million such grafts were used in the USA alone. However, the practice generally remained a “cottage industry” well into the latter part of the 20th century. This volume provides an international expert evaluaton of the current use of bone, bone substitutes and related allografts, and describes up-to-date practices and clinical results in particular procedures. It will provide a ready reference for readers wishing to carry out an initial survey of the subject.
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Clinical Applications of Bone Allografts and Substitutes Biology and Clinical Applications SERIES IN ALLOGRAFTS IN BONE HEALING: BIOLOGY AND CLINICAL APPLICATIONS Advances in Tissue Banking Specialist Publications Editor-in-Chief: Glyn O. Phillips Published Vol. 1 Bone Biology and Healing edited by Glyn O. Phillips Vol. 2 Bone Morphogenetic Protein and Collagen edited by Glyn O. Phillips Vol. 3 Clinical Applications of Allografts and Substitutes edited by Glyn O. Phillips Allografts in Bone Healing: Biology and Clinical Applications - Vol. 33 Clinical Applications of Bone (Nografts Substitutes and Biology and Clinical Applications Editor Glyn 0 Phillips Phillips Hydrocolloid Research, UK > World Scientific NEW JERSEY • LONDON • SINGAPORE • BEIJING • SHANGHAI • HONGKONG • TAIPE, . CHENNA, Published by World Scientific Publishing Co. Pte. Ltd. 5 Toh Tuck Link, Singapore 596224 USA office: 27 Warren Street, Suite 401-402, Hackensack, NJ 07601 UK office: 57 Shelton Street, Covent Garden, London WC2H 9HE British Library Cataloguing-in-Publication Data A catalogue record for this book is available from the British Library. CLINICAL APPLICATIONS OF ALLOGRAFTS AND SUBSTITUTES Copyright © 2005 by World Scientific Publishing Co. Pte. Ltd. All rights reserved. This book, or parts thereof, may not be reproduced in any form or by any means, electronic or mechanical, including photocopying, recording or any information storage and retrieval system now known or to be invented, without written permission from the Publisher. For photocopying of material in this volume, please pay a copying fee through the Copyright Clearance Center, Inc., 222 Rosewood Drive, Danvers, MA 01923, USA. In this case permission to photocopy is not required from the publisher. ISBN 981-256-343-1 Printed in Singapore by World Scientific Printers (S) Pte Ltd ALLOGRAFTS IN BONE HEALING: BIOLOGY AND CLINICAL APPLICATIONS International Advisory Board H. Burchardt, USA A. Gross, Canada M. Itoman, Japan J. Kearney, UK J. Komender, Poland B. Loty, France P. Mericka, Czech Republic D.A.F. Morgan, Australia D. Pegg, UK M. Salai, Israel W.W. Tomford, USA Y. Vajaradul, Thailand H. Winkler, Austria N. Yusof, Malaysia N. Triantafyllou, Greece R. Capanna, Italy W.W. Boeckx, Belgium C.J. Yim, Korea V CONTENTS Introduction to the Series ix Preface xiii List of Contributors xvii Chapter 1 The IAEA Code of Practice for the Radiation Sterilisation of Tissue Allografts for Validation and Routine Control Volume 7, Chapter 8 Chapter 2 Chapter 3 Chapter 4 Chapter 5 Chapter 6 Preserved Bone Allografts in Reconstructive Orthopaedics Volume 6, Paper 12 1 57 Clinical Strategy of Application of Deep Frozen Radiation Sterilised Bone Allografts Volume 6, Paper 6 67 Clinical Results and Organisat