E-Book Overview
A new subspecialty is growing at the interface of reproductive medicine and perinatology: infertility. Textbook of Periconceptional Medicine provides an authoritative and comprehensive reference source for those providing medical care to women trying to conceive a healthy pregnancy.A revolutionary first edition, Textbook of Periconceptional Medicine brings together a number of difficult, and usually separate, topics and provides the busy clinician with one authoritative and methodical reference.
E-Book Content
Periconceptional Medicine CONTENTS: PRECONCEPTION: Genetics and Conception • Lifestyle and Conception • Preconceptional Counselling ACHIEVING PREGNANCY: How to Conceive: Evidence Based Fertility Investigation • The Anovulatory Patient • The Patient with Endometriosis • The Patient with Poor Sperm Quality • The Patient with Tubal Disease • The Couple with Unexplained Infertility * The Patient from the Developing World • The Older Woman Wishing to Conceive • Psychological Aspects of Fertility Therapy • The Luteal Phase • Implantation Failure MANAGEMENT OF EARLY PREGNANCY: Early Placental Development • The Immunology of Early Pregnancy • Mechanisms and Nomenclature of Early Pregnancy Loss • Antiphospholipid Syndrome, Heritable Thrombophilia and Early Pregnancy Loss • Ultrasound in Early Pregnancy • Evidence Based Investigation and Management of Miscarriage • Ectopic Pregnancy after Fertility Treatment • Molar Pregnancy • Multiple Pregnancy • Cervical Cerclage and Pregnancy Loss • Are Pregnancies Conceived by IVF ‘High Risk’? Nick S Macklon, MD, FRCOG, is Professor of Infertility and Periconceptional Medicine and Head of Reproductive Medicine and Gynaecology at the University Medical Center, Utrecht, The Netherlands: his previous publications include IVF in the Medically Complicated Patient (Informa 2005). Ian A Greer, MD, FRCP(Glas), FRCPE, FRCP, FRCPI, FRCOG, FFFP, FMedSci, is Professor of Obstetric Medicine and Dean, Hull York Medical School, UK: his most recent publications include Maternal Medicine (Mosby 2008), Fertility and Conception (Collins 2007), Women’s Vascular Health (Arnold 2007), Practical Obstetric Hematology (Informa 2006), and Prevention of Preterm Labor (Cambridge University Press 2005). Eric AP Steegers, MD, is Professor, Obstetrics and Prenatal Medicine, Erasmus Medical Center, University Medical Center Rotterdam, The Netherlands: his previous publications include Preventive Care in Obstetrics (Baillière Tindall 1995). Cover design and image by Oxmed www.informahealthcare.com Periconceptional Medicine PREPARING THE HIGH-RISK PATIENT: The Patient with Renal Disease • The Patient with an Organ Transplant • The Patient with Hypertension • The Patient with Cardiac Disease • The Patient with Thyroid Disease • The Patient with Diabetes • The Patient with Epilepsy • The Patient at risk from Thrombosis and Bleeding Disorders • The Patient with Polycystic Ovary Syndrome • The Patient with HIV • The Patient with Cystic Fibrosis • The Patient with Inflammatory Bowel Disease • The Patient with Prolactinoma • The Patient at Risk with Severe Mental Illness • The Patient with Myotonic Dystrophy Textbook of It is inceasingly recognized that the outcome of pregnancy is largely determined during the periconceptional period. Both Perinatologists and Reproductive Endocrinologists treating couples with infertility have an important role in ensuring optimal management of this crucial, and sometimes complex, phase. At the interface between reproductive medicine, perinatology, internal medicine and genetics, the new field of Periconceptional Medicine is now emerging. This major new textbook from respected international experts provides the first major and definitive collection of work in this area, and will be of value to all those w