Regenerative Medicine, Artificial Cells and Nanomedicine – Vol. 1 ARTIFICIAL CELLS Biotechnology, Nanomedicine, Regenerative Medicine, Blood Substitutes, Bioencapsulation, and Cell/Stem Cell Therapy This page intentionally left blank Regenerative Medicine, Artificial Cells and Nanomedicine – Vol. 1 ARTIFICIAL CELLS Biotechnology, Nanomedicine, Regenerative Medicine, Blood Substitutes, Bioencapsulation, and Cell/Stem Cell Therapy Thomas Ming Swi Chang McGill University, Canada World Scientific NEW JERSEY • LONDON • SINGAPORE • BEIJING • SHANGHAI • HONG KONG • TA I P E I • CHENNAI Published by World Scientific Publishing Co. Pte. Ltd. 5 Toh Tuck Link, Singapore 596224 USA office: 27 Warren Street, Suite 401-402, Hackensack, NJ 07601 UK office: 57 Shelton Street, Covent Garden, London WC2H 9HE Library of Congress Cataloging-in-Publication Data Chang, Thomas Ming Swi. Artificial cells : biotechnology, nanomedicine, regenerative medicine, blood substitutes, bioencapsulation, cell/stem cell therapy / by Thomas Ming Swi Chang. p. ; cm. -- (Regenerative medicine, artificial cells and nanomedicine ; v. 1) Includes bibliographical references and index. ISBN-13: 978-981-270-576-1 (hardcover) -- ISBN-10: 981-270-576-7 (hardcover) ISBN-13: 978-981-270-778-9 (pbk.) -- ISBN-10: 981-270-778-6 (pbk.) 1. Artificial cells. 2. Blood substitutes.3. Nanotechnology. I. Title. II. Series. [DNLM: 1. Blood Substitutes. 2. Biotechnology. 3. Cells. 4. Nanomedicine. 5. Regenerative Medicine. WH 450 C456a 2007] RM171.7.C478 2007 615'.39—dc22 2007013738 British Library Cataloguing-in-Publication Data A catalogue record for this book is available from the British Library. Copyright © 2007 by World Scientific Publishing Co. Pte. Ltd. All rights reserved. This book, or parts thereof, may not be reproduced in any form or by any means, electronic or mechanical, including photocopying, recording or any information storage and retrieval system now known or to be invented, without written permission from the Publisher. For photocopying of material in this volume, please pay a copying fee through the Copyright Clearance Center, Inc., 222 Rosewood Drive, Danvers, MA 01923, USA. In this case permission to photocopy is not required from the publisher. Typeset by Stallion Press Email:
[email protected] Printed in Singapore. SC - Artificial Cells.pmd 1 6/8/2007, 2:10 PM April 13, 2007 13:48 SPI-B446 Artificial Cells: Biotechnology, Nanotechnology, Blood Substitutes, Regenerative... Dedication My wife, Lancy, for her selfless dedication, moral support and encouragement throughout my 50 years of research on artificial cells. My children, Harvey, Victor, Christine and Sandra. My grandchildren, Josh, Jared, Micaela, Matthew, Emma and Katya. v fm April 13, 2007 13:48 SPI-B446 Artificial Cells: Biotechnology, Nanotechnology, Blood Substitutes, Regenerative... This page intentionally left blank fm April 13, 2007 13:48 SPI-B446 Artificial Cells: Biotechnology, Na