Science (vol. 307, No. 5708, January 2005)

21 January 2005 Vol. 307 No. 5708 Pages 301–464 $10 Explore Phosphorylation with BioSource Control FAK Paxillin JNK HSP27 Control EGFR Src Akt p38 ATF2 CREB Explore Kinase pathways with easy-to-use Mercator ™ PhosphoArray Mercator ™ PhosphoArray Features and Advantages Using a patented technology to achieve increased binding capacity, this glass- • • • • • • • phosphorylation status of key regulatory sites is measured using a panel of phosphorylation site-specific antibodies. The use of in-house manufactured antibodies, and recombinant protein standards allows accurate, reproducible and quantitative measurements. Simultaneously measure phosphorylation of 10 intracellular proteins Rapid results in 5 hours Available in 1- and 4-slide kits (up to 16 samples per slide) Quantitative multiplexed standards available separately Compatible with most glass slide array readers High precision (CV