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4 March 2005 Vol. 307 No. 5714 Pages 1357–1516 $10 COVER Artist’s view of a human T cell as a globe, with the chemokine CCL3L1 shielding the cell from infection by HIV-1 (circles with red spikes) by virtue of its interaction with the HIV coreceptor CCR5 (yellow). CCL3L1 is represented by green circles emanating from green bands on chromosome 17, with the intensity indicating differences in gene dose (fluorescence in situ hybridization courtesy of Robin Leach). See page 1434. [Image: S. K.Ahuja and D. Baker] DEPARTMENTS 1369 1371 1375 1377 1382 1385 1481 1488 SCIENCE ONLINE THIS WEEK IN SCIENCE EDITORIAL by Donald Kennedy Bayh-Dole: Almost 25 EDITORS’ CHOICE CONTACT SCIENCE NETWATCH NEW PRODUCTS SCIENCE CAREERS 1399 CONSERVATION SCIENCE What’s in a Species’ Name? More Than $450,000 1401 U.S. POLAR RESEARCH Shift in Icebreaking Fleet Could Crunch NSF Budget 1402 MATHEMATICS What in the Name of Euclid Is Going On Here? Have a Coq and a Smile 1405 1409 PALEOANTHROPOLOGY Small but Smart? Flores Hominid Shows Signs of Advanced Brain “Hobbit” Bones Go Home to Jakarta 1396 & 1409 related Science Express Report by D. Falk et al. 1387 RANDOM SAMPLES LETTERS NEWS OF THE WEEK 1386 Volume 307 4 March 2005 Number 5714 PLANETARY SCIENCE A Strange Little Saturnian Ice Ball Gets Stranger Still 1389 COMPUTER SECURITY Flaw Found in Data-Protection Method 1389 SCIENCESCOPE 1390 PLANETARY SCIENCE Ice or Lava Sea on Mars? A Transatlantic Debate Erupts S. Altman et al.: related News story page 1396 BOOKS ET AL. 1413 CONFLICTS OF INTEREST NIH Scientists Raise Fuss About Scope of New Rules 1391 FRENCH SCIENCE Report Puts Pasteur M