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Table of Contents Medical Research and Ethics in 4 February 2005 Mali Volume 307 Number 5710 Understanding the PermianTriassic Extinction Why Hair Turns Gray Insights into Crohn's Disease Gordon Research Conferences RESEARCH This Week in Science Fungus Monoculture on the Ant Farm * Saturnian Hot Spot * Two's Company, Three's a Cloud? * The End of the Line * Glimpses into the P/T Boundary * Protein Kinase Inhibition Revealed * A Matter of Scale * Packaging and Power Combining * Fade to Gray * Autophagic Arms Race * Giving Mice the Nod * Cytokine Production and Kaposi's * Deconstructing Dislocations * A Matter of Timing? 641 Editors' Choice: Highlights of the recent literature EPIDEMIOLOGY: Don't Keep Hedgehogs * CELL BIOLOGY: Popeye's Ribosomes * CHEMISTRY: Unlocking Fluorescence * GEOLOGY: Protection Against Erosion * BEHAVIOR: Less Editing, Less Depression * EARTH SCIENCE: Getting a Fix on Fixation * STKE: Balancing Axons and Dendrites 646 Brevia Simple Foraminifera Flourish at the Ocean's Deepest Point Yuko Todo, Hiroshi Kitazato, Jun Hashimoto, and Andrew J. Gooday 689. Research Article Crystal Structure of a Complex Between the Catalytic and Regulatory (RI ) Subunits of PKA Choel Kim, Nguyen-Huu Xuong, and Susan S. Taylor 690-696. Saturn's Temperature Field from High-Resolution Middle-Infrared Imaging G. S. Orton and P. A. Yanamandra-Fisher 696-698. Reports Rapid Formation of Sulfuric Acid Particles at Near-Atmospheric Conditions Torsten Berndt, Olaf Böge, Frank Stratmann, Jost Heintzenberg, and Markku Kulmala 698-700. Dislocations in Complex Materials Matthew F. Chisholm, Sharvan Kumar, and Peter Hazzledine 701-703. End States in One-Dimensional Atom Chains J. N. Crain and D. T. Pierce 703-706. Photic Zone Euxinia During the Permian-Triassic Superanoxic Event Kliti Grice, Changqun Cao, Gordon D. Love, Michael E. Böttcher, Richard J. Twitchett, Emma