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Volume 437 Number 7061 pp927-1064 In this issue (13 October 2005) • • • • • • Editorials Research Highlights News News Features Business Correspondence Also this week • Editor's Summary • Authors • Nature Podcast • Books and Arts • News and Views • Brief Communications • Articles • Letters • Naturejobs • Futures Editorials Peace and honour p927 The 2005 Nobel Peace Prize is a timely reminder of the good work done by the International Atomic Energy Agency and its director, Mohamed ElBaradei. From rhetoric to reality p927 President Bush's acknowledgement of the threat of pandemic flu is welcome, if belated. Advise the president p928 The merger of two White House advisory panels sends out the wrong message. Research Highlights Research highlights p930 News US progressives fight for a voice in bioethics p932 Left-leaning think-tank aims to influence political decisions. Erika Check Nuclear group nabs peace prize p932 Jim Giles Sidelines p933 More evidence for hobbit unearthed as diggers are refused access to cave p934 Excavations shed light on lifestyle of Homo floresiensis. Rex Dalton Indonesia struggles to control bird flu outbreak p937 As officials in Washington discuss how to tackle outbreaks of bird flu more effectively (see From rhetoric to reality ), an outbreak in humans continues in Asia. Declan Butler assesses the situation in Indonesia, and finds out how likely it is that the virus might evolve into a pandemic strain. Declan Butler Chemical exchange captures Nobel p938 Prize goes to trio who transformed organic synthesis. Philip Ball Ig Nobels hail world's longest-running experiment p938 Distinguished scientists gather in Boston for silliness awards. Steve Nadis News in brief p940 Correction p940 News Features Drug discovery: Playing dirty p942 Forget drugs carefully designed to hit one particular molecule — a better way of treating complex diseases such as cancer