E-Book Overview
The events of September 11, 2001 have clearly demonstrated that the future pathologies of warfare will increasingly affect noncombatant populations on a large scale and require new levels of treatment expertise. In Combat Medicine: Basic and Clinical Research in Military, Trauma, and Emergency Medicine, highly accomplished clinical and basic investigators concisely review the leading research issues confronting emergency and military medicine today. These experts begin by presenting the latest thinking about the molecular and cellular mechanisms of trauma-apoptosis, abnormalities in nitric oxide production, complement activation, and immune cell response to stressors-that lead to tissue damage, and then describe cutting-edge research aimed at understanding and reversing the consequent damage to major organs. The clinical conditions covered include hemorrhagic shock and resuscitation, ischemia-reperfusion injury, acute respiratory distress syndrome, thermal injury, inhalation injury, and traumatic brain injury. The authors discuss the natures of combat pathologies, current research, emerging treatments, red blood cell storage, and bioterrorism involving anthrax, smallpox, plague, and other infectious and toxic agents. Cutting-edge and timely, Combat Medicine: Basic and Clinical Research in Military, Trauma, and Emergency Medicine offers not only clinical and basic investigators, but also surgical and medical residents, a concise introduction to the principal clinical conditions encountered in emergency, disaster, and combat medicine, as well as an up-to-date statement of where our diagnostic and treatment programs now stand, and what we still need to learn for future preparedness.
E-Book Content
Combat Medicine Combat Medicine Basic and Clinical Research in Military, Trauma, and Emergency Medicine Edited by George C. Tsokos, MD James L.Atkins, MD Walter Reed Army Institute of Research Silver Spring, MD *- Springer Science+Business Media, LLC © 2003 Springer Science+Business Media New York Originally published by Humana Press Inc in 2003. Softcover reprint of the hardcover 1st edition 2003 www.humanapress.com Ali rights reserved. No pari of this book may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying, microfilming, recording, or otherwise without written permission from the Publisher. The content and opinions expressed in this book are the sole work of the authors and editors, who have warranted due diligence in the creation and issuance of their work. The publisher, editors, and authors are not responsible for errors or omissions or for any consequences arising from the information or opinions presented in this book and make no warranty, express or implied, with respect to its contents. Due diligence has been taken by the publishers, editors, and authors of this book to assure the accuracy of the information published and to describe generally accepted practices. The contributors herein have carefully checked to ensure that the drug selections and dosages set forth in this text are accurate and in accord with the standards accepted at the time of publication. Notwithstanding, as new research, changes in government regulations, and knowledge from clinical experience relating to drug therapy and drug reactions constant1y occurs, the reader is advised to check the product information provided by the manufacturer of each drug for any change in dosages or for additional wamings and contraindications. This is of utmost importance when the recommended drug herein is a new or infrequent1y used drug. It is the responsibility of the treating physician to determine dosages and treatment strategies for individual patients. Further it is the responsibility of the health care provider to ascert