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The 25th Jerusalem Symposium represents a most significant highlight in the development and history of these meetings. Living within the decimal system we have celebrated with much pleasure the lath and the 20th Jerusalem Symposia. With this one we experience a feeling of particular satisfaction because 25 years is different from, is more than, two decades and a half. It is a quarter of a century. It seems thus as if we have changed the dimension of our endeavour. In no way do we loose the sense of modesty with respect to the significance of these meetings. For the organizers, however, they do represent a continuity of efforts which we feel happy to have been able to carry out. At this occasion it seems useful to say a few words about the origin of the Jerusalem Symposia and to recall the name of a colleague who played an essential role in their creation and has been a most efficient and devoted co organizer of the seven first of them. This was Professor Ernst Bergmann, one of the most distinguished founders of Israeli Science and a world famous physico-organic chemist.
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MEMBRANE PROTEINS: STRUCTURES, INTERACTIONS A N D MODELS THE JERUSALEM SYMPOSIA O N QUANTUM CHEMISTRY A N D BIOCHEMISTRY Published by the Israel Academy of Sciences and Humanities, distributed by Academic Press (N.Y.) 1. The Physicochemical Aspects of Carcinogenesis (October 1968) 2. Quantum Aspects of Heterocyclic Compounds in Chemistry and Biochemistry (April 1969) 3. Aromaticity, Pseudo-Aromaticity, Antiaromaticity (April 1970) 4. The Purines: Theory and Experiment (April 1971) 5. The Conformation of Biological Molecules and Polymers (April 1972) Published by the Israel Academy of Sciences and Humanities, distributed by D. Reidel Publishing Company (Dordrecht, Boston, Lancaster, and Tokyo) 6. Chemical and Biochemical Reactivity (April 1973) Published and distributed by D. Reidel Publishing Company (Dordrecht, Boston, Lancaster, and Tokyo) 7. Molecular and Quantum Pharmacology (March/April 1974) 8. Environmental Effects on Molecular Structure and Properties (April 1975) 9. Metal-Ligand Interactions in Organic Chemistry and Biochemistry (April 1976) 10. Excited States in Organic Chemistry and Biochemistry (March 1977) 11. Nuclear Magnetic Resonance Spectroscopy in Molecular Biology (April 1978) 12. Catalysis in Chemistry and Biochemistry Theory and Experiment (April 1979) 13. Carcinogenesis: Fundamental Mechanisms and Environmental Effects (April/May 1980) 14. Intermodular Forces (April 1981) 15. Intermodular Dynamics (Maart/April 1982) 16. Nucleic Acids: The Vectors of Life (May 1983) 17. Dynamics on Surfaces (April/May 1984) 18. Interrelationship Among Aging, Cancer and Differentiation (April/May 1985) 19. Tunneling (May 1986) 20. Large Finite Systems (May 1987) Published and distributed by Kluwer Academic Publishers (Dordrecht, Boston, London) 21. Transport through Membranes: Carriers, Channels and Pumps (May 1988) 22. Perspectives in Photosynthesis (May 1989) 23. Molecular Basis of Specificity in Nucleic Acid-Drug Interaction (May 1990) 24. Mode Selective Chemistry (May 1991) 25. Membrane Proteins: Structures, Interactions and Models (May 1992) V O L U M E 25 MEMBRANE PROTEINS: STRUCTURES, INTERACTIONS AND MODELS PROCEEDINGS OF T H E T W E N T Y - F I F T H J E R U S A L E M S Y M P O S I U M O N Q U A N T U M C H E M I S T R Y A N D BIOCHEMISTRY H E L D IN J E R U S A L E M , ISRAEL, M A Y IS—21» 1992 Edited by ALBERTE P U L L M A N Institut de Biologie Physico-Chimique (Fondation Edmond de Rothschild), Paris, France JOSHUA JORTNER Department of Chemistry, University of Tel-Aviv, Israel and BERNARD P U L L M A N Institut de Biologie Physico-Chimique (Fondation Edmond de Rothschild), Pahs, France SPRINGER SCIENCE+BUSINESS MEDIA, B.V. Library of Cong