Vaccines Against Virally Induced Cancers (novartis Foundation Symposia)

VACCINES AGAINST VIRALLY INDUCED CANCERS The Ciba Foundation is an international scientific and educational charity (Registered Charity No. 313574). It was established in 1947 by the Swiss chemical and pharmaceutical company of ClBA Limited-now Ciba-Geigy Limited. The Foundation operates independently in London under English trust law. The Ciba Foundation exists to promote international cooperation in biological, medical and chemical research. It organizes about eight international multidisciplinary symposia each year on topics that seem ready for discussion by a small group of research workers. The papers and discussions are published in the Ciba Foundation symposium series. The Foundation also holds many shorter meetings (not published), organized by the Foundation itself or by outside scientific organizations. The staff always welcome suggestions for future meetings. The Foundation’s house at 41 Portland Place, London W1N 4BN, provides facilities for meetings of all kinds. Its Media Resource Service supplies information to journalists on all scientific and technological topics. The library, open five days a week to any graduate in science or medicine, also provides information on scientific meetings throughout the world and answers general enquiries on biomedical and chemical subjects. Scientists from any part of the world may stay in the house during working visits to London. Ciba Foundation Symposium 187 VACCINES AGAlNST VIRALLY INDUCED CANCERS 1994 JOHN WILEY & SONS Chichester . New York . Brisbane Toronto . Singapore OCiba Foundation 1994 Published in 1994 by John Wiley & Sons Ltd Baffins Lane, Chichester West Sussex PO19 IUD, England Telephone National Chichester (0243) 779777 International ( + 44) (243) 779777 All rights reserved. No part of this book may be reproduced by any means, or transmitted, or translated into a machine language without the written permission of the publisher. Other Wiley Editorial Of$ces John Wiley & Sons, Inc., 605 Third Avenue, New York, NY 10158-0012, USA Jacaranda Wiley Ltd, G.P.O. Box 859, Brisbane, Queensland 4001, Australia John Wiley & Sons (Canada) Ltd, 22 Worcester Road, Rexdale, Ontario M9W 1L1, Canada John Wiley & Sons (SEA) Pte Ltd, 37 Jalan Pemimpin #05-04, Block B, Union Industrial Building, Singapore 2057 Suggested series entry for library catalogues: Ciba Foundation Symposia Ciba Foundation Symposium 187 xi+281 pages, 32 figures, 13 tables Library of Congress Cataloging-in-PublicationData Vaccines against virally induced cancers. p. cm.-(Ciba Foundation symposium; 187) Includes bibliographical references and index. ISBN 0 471 95026 2 I . Viral carcinogenesis-Congresses. 2. Viral vaccinesCongresses. 3. Cancer-lmmunotherapy-Congresses. I. Frazer, I. H. (Ian H.) 11. Series. [ DNLM: 1. Neoplasms-immunology-congresses. 2. Tumor Virus Infections-immunology-congresses. 3. Vaccines-immunologycongresses. 4. Oncogenic Viruses-pathogenicity-congresses. W3 C161F v. 187 1994 / 42200 V116 19941 RC268.57,V33 1994 616.99' 4079-dc20 DNLM/DLC for Library of Congress 94-33207 CIP British Library Cataloguing in Publication Data A catalogue record for this book is available from the British Library ISBN 0 471 95026 2 Phototypeset by Dobbie Typesetting Limited, Tavistock, Devon. Printed and bound in Great Britain by Biddles Ltd, Guildford. Contents Symposium on Vaccines against virally induced cancers, held at the Ciba Foundation, London, 15-1 7 March 1994 This symposium is based on a proposal made by Ian Frazer Editors: Derek J. Chadwick (Organizer) and Joan Marsh I.