Innovative Endocrinology Of Cancer

Innovative Endocrinology of Cancer ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY Editorial Board: NATHANBACK., State University ofNew Yorkat Buffalo IRUN R. COHEN, The Weizmann Institute ofScience ABEL LAJTHA, N'S. Kline Institutefor PsychiatricResearch JOHN D. LAMBRIS, University ofPennsylvania RODOLFOPAOLETTI, University ofMilan Recent Volumes in this Series Volume622 OVARIAN CANCER Edited by George Coukos,Andrew Berchuck,and Robert Ozols Volume 623 ALTERNATIVE SPLICINGIN THE POSTGENOMIC ERA Edited by Benjamin 1. Blencowe and Brenton R. Graveley Volume 624 SUNLIGHT, VITAMIN D AND SKIN CANCER Edited by Jorg Reichrath Volume625 DRUG TARGETS IN KINETOPLASTID PARASITES Edited by Hemanta K. Majumder Volume 626 GENOMICIMPRINTING Edited by Jon F. Wilkins Volume 627 TRANSGENESIS AND THE MANAGEMENT OF VECTOR-BORNE DISEASE Edited by SerapAksoy Volume 628 BRAIN DEVELOPMENT IN DROSOPHILA MELANOGASTER Edited by GerhardM. Technau Volume 629 PROGRESSIN MOTORCONTROL Edited by Dagmar Sternad Volume 630 INNOVATIVE ENDOCRINOLOGY OF CANCER Edited by Lev M. Berstein and Richard 1. Santen A Continuation Order Plan is availablefor this series.A continuationorder will bring delivery of each new volume immediatelyupon publication.Volumes are billed only upon actual shipment.For further information please contact the publisher. Innovative Endocrinology of Cancer Edited by Lev M. Berstein, MD, PhD, DMS Laboratory ofOncoendocrinology, Professor N.N. Petrov Research Institute ofOncology, St. Petersburg, Russia Richard J. Santen, MD Division ofEndocrinology and Metabolism, University of Virginia Health Sciences Center, Charlottesville, Virginia, USA Springer Science+Business Media, LLC Landes Bioscience SpringerScience+Business Media,LLC LandesBioscience Copyright©2008LandesBioscienceand SpringerScience+Business Media,LLC All rights reserved. No partof thisbookmay bereproducedor transmitted in anyformor by anymeans,electronic or mechanical, includingphotocopy, recording,or any information storageandretrievalsystem,withoutpermission in writing fromthe publisher, with the exceptionof any materialsuppliedspecifically for the purposeof being enteredand executedon a computersystem;for exclusiveuse by the Purchaserof the work. Printedin the U.S.A. SpringerScience+Business Media,LLC, 233 Spring Street,New York, New York10013,USA http://www.springer.com Please addressall inquiriesto the publishers: LandesBioscience, 1002WestAvenue, 2nd Floor,Austin,Texas78701,USA Phone: 512/637 5060; FAX: 512/6376079 http://www.landesbioscience.com Innovative Endocrinology of Cancer, edited by Lev M. Berstein and Richard J. Santen, Landes Bioscience 1 Springer Science+Business Media, LLC dual imprint 1 Springerseries:Advances in Experimental Medicineand Biology ISBN: 978-0-387-78817-3 Whilethe authors,editorsandpublisherbelievethatdrug selectionand dosageand the specifications and usage of equipmentand devices, as set forth in this book, are in accord with current recommendations and practice at the time of publication, they make no warranty, expressed or implied, with respect to material described in this book. In view of the ongoing research, equipmentdevelopment, changes in governmental regulationsand the rapid accumulation of information relatingto the biomedicalsciences, the reader is urged to carefullyreview and evaluatethe informationprovidedherein. Library of Congress Catalog