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Traditionally the International Congress of Parkinson’s Disease and Related disorders (ICPD) is reflected in publishing its proceedings. This is to (1) sum up the current knowledge in this particular spectrum disorder and (2) to remind clinicians and basic researchers on the development and progress made overtime with respect to etiology, pathology, genetics, endogenous vulnerability factors, models, drug treatment strategies, e.g. levodopa, neuroprotective drugs, new developments in neurotherapeutics, neurosurgery, plasticity of nerve cell structures and clinical issues (e.g. staging, early diagnosis, differential diagnostic aspects, clinico-pathological correlations, new scales etc.). All these topics that have been brought forward at the 16. ICPD congress 2005, Berlin, are now available in a subsumed version in supplementum 70 of Journal Neural Transmission. This book gives a comprehensive overview on current clinical and basic research issues related to Parkinson’s disease and its related disorders and is suitable for neurologists, psychiatrists, neurosurgeons, basic researchers, geneticists and patients as well as their relatives.
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W P. Riederer, H. Reichmann, M. B. H. Youdim, M. Gerlach (eds.) Parkinson’s Disease and Related Disorders Journal of Neural Transmission Supplement 70 SpringerWienNewYork Prof. Dr. P. Riederer Klinik und Poliklinik für Psychiatrie und Psychotherapie Würzburg, Germany Prof. Dr. H. Reichmann Universitätsklinikum der TU Dresden Dresden, Germany Prof. Dr. M. B. H. Youdim Israel Institute of Technology Haifa, Israel Prof. Dr. M. Gerlach Klinik und Poliklinik für Psychiatrie und Psychotherapie Würzburg, Germany This work is subject to copyright. $OO ULJKWV DUH UHVHUYHG ZKHWKHU WKH ZKROH RU SDUW RI WKH PDWHULDO LV FRQFHUQHG VSHFL¿FDOO\ those of translation, reprinting, re-use of illustrations, broadcasting, reproduction by photocopying machines or similar means, and storage in data banks. Product Liability: The publisher can give no guarantee for the information contained in this book. This also refers to that on drug dosage and application thereof. In each individual case the respective user must check the accuracy of the information given by consulting other pharmaceutical literature. The use of registered names, trademarks, etc. in this publication GRHV QRW LPSO\ HYHQ LQ WKH DEVHQFH RI VSHFL¿F VWDWHPHQW WKDW VXFK QDPHV DUH H[HPSW IURP the relevant protective laws and regulations and therefore free for general use. © 2006 Springer-Verlag/Wien Printed in Austria SpringerWienNewYork is part of Springer Science+Business Media springer.com Typesetting: Thomson Press India Ltd., New Dehli Printing: Druckerei Theiss GmbH, 9431 St. Stefan im Lavanttal, Austria Printed on acid-free and chlorine-free bleached paper SPIN: 11516439 Library of Congress Control Number: 2006928439 With 75 Figures ISSN 0303-6995 ISBN-10 3-211-28927-5 SpringerWienNewYork ISBN-13 978-3-211-28927-3 SpringerWienNewYork J Neural Transm (2006) [Suppl] 70: V–VI # Springer-Verlag 2006 Preface It is our pleasure to present the Proceedings of the 16th International Congress on Parkinson’s Disease (PD) and Related Disorders (16th ICPD) which took place in Berlin from June 5–9, 2005. This congress was the most successful congress ever with more than 3500 participants in the roaring German capital, consisting of an innovative program and with emphasis on bringing basic and clinical scientists together. Special attention has was paid in inviting young scientists. Therefore, the major aspect of scientific sessions was to identify young and up coming individuals in the field, with novel approaches to PD and novel models as a whole. The congress gave us the opportunity to present Germany and its capital after the burde