Advances in Heterocyclic Chemistry Volume 63 Editorial Advisory Board R. A. Abramovitch, Clemson, South Carolina A. T. Balaban, Bucharest, Romania A. J. Boulton, Norwich, England H. Dorn, Berlin-Bohnsdorf, Germany J. Elguero, Madrid, Spain S. Gronowitz, Lund, Sweden E. Lukevics, Riga, Latvia 0. Meth-Cohn, Sunderland, England V. I. Minkin, Rostov-on-Don, Russia C. W. Rees, FRS, London, England E. F. V. Scriven, Indianapolis, Indiana D. StC. Black, New South Wales, Australia E. C . Taylor, Princeton, New Jersey M. TiSler, Ljubljana, Slovenia J. A. Zoltewicz, Gainesville, Florida Advances in HETEROCYCLIC CHEMISTRY Edited by ALAN R. KATRITZKY, FRS Kenan Professor of Chemistry Department of Chemistry University of Florida Gainesville, Florida Volume 63 ACADEMIC PRESS San Diego New York Boston London Sydney Tokyo Toronto This book is printed on acid-free paper. @ Copyright 0 1995 by ACADEMIC PRESS, INC. All Rights Reserved. No part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher. Academic Press, Inc. A Division of Harcourt Brace & Company 525 B Street, Suite 1900, San Diego, California 92101-4495 United Kingdom Edition published by Academic Press Limited 24-28 Oval Road, London NW 1 7DX International Standard Serial Number: 0065-2725 International Standard Book Number: 0- 12-020763-X PRINTED IN THE UNITED STATES OF AMERICA 95 96 9 7 9 8 99 0 0 B B 9 8 7 6 5 4 3 2 1 Contents CONTRIBUTORS............................................................... PREFACE ..................................................................... vii ix Six-Membered Heterocycles with a Tellurium Atom IGOR D. SADEKOV AND VLADIMIR I. MINKIN I. Introduction ............................................................. 11. Monocyclic, Bicyclic, and Tricyclic Tellurium-Containing Heterocycles with Tellurium Atoms in Position 1 ...................................... 111. Bicyclic Six-Membered Heterocycles with a Tellurium Atom in Position 2 ............................................................ References .............................................................. 2 3 53 55 Annelated 1,5-Benzothiazepines A. CHIMIRRI, R. GITTO,S. GRASSO,A. M. MONFORTE,AND M. ZAPPALA I. Introduction ............................................................. 11. Tricyclic 1,5-Benzothiazepines ........................................... 111. Tetracyclic 1,5-Benzothiazepines ........................................ References .............................................................. 62 63 88 98 Recent Developments in the Chemistry of Pyrido[ 1,Za]pyrimidines ISTVANHERMECZ I. Introduction ............................................................. Physicochemical Properties of Pyrido[1,2-a]pyrimidines .................. Reparation of Pyrido[ 1,2-~]pyrirnidines .................................. Reactions of Pyrido[1,2-a]pyrirnidines .................................... Applications of Pyrido[1,2-a]pyrimidines ................................. Appendix ............................................................... References .............................................................. 11. 111. IV. V. VI. V 104 106 124 169 24 1 248 25