Genetics of Sexual Differentiation and Sexually Dimorphic Behaviors
Advances in Genetics, Volume 59
Serial Editors
Jeffery C. Hall Waltham, Massachusetts
Jay C. Dunlap Hanover, New Hampshire
Theodore Friedmann La Jolla, California
Veronica van Heyningen Edinburgh, United Kingdom
Genetics of Sexual Differentiation and Sexually Dimorphic Behaviors Edited by
Daisuke Yamamoto Division of Neurogenetics Graduate School of Life Sciences Tohoku University Sendai, Japan
AMSTERDAM • BOSTON • HEIDELBERG • LONDON NEW YORK • OXFORD • PARIS • SAN DIEGO SAN FRANCISCO • SINGAPORE • SYDNEY • TOKYO Academic Press is an imprint of Elsevier
Academic Press is an imprint of Elsevier 84 Theobald’s Road, London WC1X 8RR, UK Radarweg 29, PO Box 211, 1000 AE Amsterdam, The Netherlands Linacre House, Jordan Hill, Oxford OX2 8DP, UK 30 Corporate Drive, Suite 400, Burlington, MA 01803, USA 525 B Street, Suite 1900, San Diego, CA 92101-4495, USA
First edition 2007 Copyright ß 2007 Elsevier Inc. All rights reserved
No part of this publication may be reproduced, stored in a retrieval system or transmitted in any form or by any means electronic, mechanical, photocopying, recording or otherwise without the prior written permission of the publisher Permissions may be sought directly from Elsevier’s Science & Technology Rights Department in Oxford, UK: phone (+44) (0) 1865 843830; fax (+44) (0) 1865 853333; email:
[email protected] Alternatively you can submit your request online by visiting the Elsevier web site at http://elsevier.com/locate/permissions, and selecting Obtaining permission to use Elsevier material Notice No responsibility is assumed by the publisher for any injury and/or damage to persons or property as a matter of products liability, negligence or otherwise, or from any use or operation of any methods, products, instructions or ideas contained in the material herein. Because of rapid advances in the medical sciences, in particular, independent verification of diagnoses and drug dosages should be made ISBN: 978-0-12-017660-1 ISSN: 0065-2660 For information on all Academic Press publications visit our website at books.elsevier.com
Printed and bound in USA 07 08 09 10 11 10 9
8 7 6 5
4 3 2 1
Contents Contributors Preface xi
ix
1 Genetic Control of Sex Differences in C. elegans Neurobiology and Behavior 1 Douglas S. Portman I. Introduction II. Main Text III. Conclusions References
2 4 29 31
2 The Neural and Genetic Substrates of Sexual Behavior in Drosophila 39 Daisuke Yamamoto I. Hypothesis on the Master Control Gene for Behavior II. Discovery of fru Mutants and Their Phenotypic Characteristics 42 III. Molecular Biology of fru Locus 49 IV. Cellular Basis of fru Functions in Male Courtship Behavior 53 V. Conclusions 58 References 59
40
3 Sexual Differentiation of the Vocal Control System of Birds 67 Manfred Gahr I. II. III. IV.
Introduction 68 Sex-Specific and Sex-Typical Vocalizations 70 The Endocrinology of Birds’ Vocalization 72 Steroid Sensitivity of the Vocal Control System of Afferent Auditory Regions and Modulatory Systems 75 V. Sexual Dimorphisms of the Vocal Control System of Songbirds 84 v
vi
Contents
VI. Sexual Differentiation of the Vocal Control System of Songbirds 87 VII. Sexual Differentiation of Vocal Control Areas in Adulthood 91 References 94
4 Gene Regulation as a Modulator of Social Preference in Voles 107 Elizabeth A. D. Hammock I. II. III. IV.
Introduction 108 Oxytocin and Pair Bonding in Voles 110 Vasopressin and Pair Bonding in Voles 111 Gene Regulation in Male Species-Ty