Hematopoietic Stem Cell Transplantation In Clinical Practice

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A guide to the practice of stem cell transplantation, its status in the treatment of various disorders and the problems that arise after transplantation, aimed at the whole transplant team.An up to date guide to best practice in the use of stem cell transplantation, covering current status in the treatment of malignant and non-malignant conditions, practical aspects and problems such as infection and graft versus host disease.Has a practical, accessible approach with free use of algorithms, list tables.Aimed at the whole transplant team - this is an interdisciplinary field.International contributor team with editors in the UK and USA.Illustrated in colour throughout.

E-Book Content

© 2009, Elsevier Limited. All rights reserved. No part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, recording, or any information storage and retrieval system, without permission in writing from the publisher. Permissions may be sought directly from Elsevier’s Rights Department: phone: (+1) 215 239 3804 (US) or (+44) 1865 843830 (UK); fax: (+44) 1865 853333; email: [email protected] You may also complete your request online via the Elsevier website at www.elsevier. com/permissions. First published 2009 ISBN: 978-0-443-10147-2 British Library Cataloguing in Publication Data A catalogue record for this book is available from the British Library Library of Congress Cataloging in Publication Data A catalog record for this book is available from the Library of Congress Notice Knowledge and best practice in this field are constantly changing. As new research and experience broaden our knowledge, changes in practice, treatment and drug therapy may become necessary or appropriate. Readers are advised to check the most current information provided (i) on procedures featured or (ii) by the manufacturer of each product to be administered, to verify the recommended dose or formula, the method and duration of administration, and contraindications. It is the responsibility of the practitioner, relying on their own experience and knowledge of the patient, to make diagnoses, to determine dosages and the best treatment for each individual patient, and to take all appropriate safety precautions. To the fullest extent of the law, neither the Publisher nor the Editors assume any liability for any injury and/or damage to persons or property arising out or related to any use of the material contained in this book. Neither the Publisher nor the Editors assume any responsibility for any loss or injury and/or damage to persons or property arising out of or related to any use of the material contained in this book. It is the responsibility of the treating practitioner, relying on independent expertise and knowledge of the patient, to determine the best treatment and method of application for the patient. The Publisher Working together to grow libraries in developing countries www.elsevier.com | www.bookaid.org | www.sabre.org Printed in China The publisher’s policy is to use paper manufactured from sustainable forests Table of Contents PART 1. SETTING THE SCENE Introduction. Essential biology of stem cell transplantation PART 2. THE ROLE OF STEM CELL TRANSPLANTATION IN TREATMENT Acute myeloid leukaemia. Chronic myeloid leukaemia. Acute lymphoblastic leukemia in adults. Childhood leukemias. The myelodysplastic syndromes. Multiple myeloma. Hodgkin’s disease and non-Hodgkin's lymphoma. Chronic lymphocytic leukaemia. Solid tumors in children. Breast cancer. Solid tumors in adults. Germ cell tumors. Primary immunodeficiency diseases. Acquired aplastic anemia and Fanconi anemia. Thalassaemia and sickle cell disease. Lys
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