E-Book Overview
This authoritative reference brings together current knowledge in the field of respiratory genetics in a single volume for the first time. The book includes a comprehensive introductory section to provide guidance and aid understanding of key basic concepts in respiratory genetics, including statistical methods, sample collection and storage, bioinformatics, and molecular genetics. This is followed by a series of disease-specific chapters which review epidemiology; natural history; monogenic components and complex traits where relevant; disease management, including genetic counseling issues; and likely future developments. Chapters are written in a uniform structure--ensuring consistency of approach throughout--and each concludes with a summary highlighting practical ''take-home'' messages regarding patient management for the reader. It is also highly illustrated, including color plates where appropriate.
E-Book Content
Respiratory Genetics
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Respiratory Genetics
Edited by Edwin K. Silverman MD, PhD Channing Laboratory and Division of Pulmonary and Critical Care Medicine Brigham and Women’s Hospital Harvard Medical School Boston, MA USA
Scott T. Weiss MD, MS Channing Laboratory Brigham and Women’s Hospital Harvard Medical School Boston, MA USA
David A. Lomas PhD, ScD, FRCP, FMedSci Department of Medicine University of Cambridge Cambridge Institute for Medical Research Cambridge, UK
Steven D. Shapiro MD Division of Pulmonary and Critical Care Medicine Brigham and Women’s Hospital Harvard Medical School Boston, MA USA
First published in Great Britain in 2005 by Hodder Education, a member of the Hodder Headline Group, 338 Euston Road, London NW1 3BH http://www.hoddereducation.com Distributed in the United States of America by Oxford University Press Inc., 198 Madison Avenue, New York, NY10016 Oxford is a registered trademark of Oxford University Press © 2005 Edward Arnold (Publishers) Ltd All rights reserved. Apart from any use permitted under UK copyright law, this publication may only be reproduced, stored or transmitted, in any form, or by any means with prior permission in writing of the publishers or in the case of reprographic production in accordance with the terms of licences issued by the Copyright Licensing Agency. In the United Kingdom such licences are issued by the Copyright Licensing Agency: 90 Tottenham Court Road, London W1T 4LP. Whilst the advice and information in this book are believed to be true and accurate at the date of going to press, neither the author[s] nor the publisher can accept any legal responsibility or liability for any errors or omissions that may be made. In particular, (but without limiting the generality of the preceding disclaimer) every effort has been made to check drug dosages; however it is still possible that errors have been missed. Furthermore, dosage schedules are constantly being revised and new side-effects recognized. For these reasons the reader is strongly urged to consult the drug companies’ printed instructions before administering any of the drugs recommended in this book. British Library Cataloguing in Publication Data A catalogue record for this book is available from the British Library Library of Congress Cataloging-in-Publication Data A catalog record for this book is available from the Library of Congress ISBN 0 340 814322 1 2 3 4 5 6 7 8 9 10 Commissioning Editor: Project Editor: Production Controller: Cover Design: Index:
Joanna Koster Naomi Wilkinson Lindsay Smith Sarah Rees Dr Laurence Errington
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