Proteins: Analysis and Design focuses solely on individual experimental approaches, rather than on specific classes of proteins. The book provides insight into the important issues in protein science and how one can cope with them. These include all issues which explore the detailed relationship of protein structure to function. Key Features: * Provides problems and technical solutions * Includes posttranslational modifications * Uses synthetic peptides as biological models * Details mutagenesis and protein engineering * Covers design of protein structure and function
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Proteins Analysis and Design
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Front cover photograph: Alpha carbon trace of trimeric tetrahydrodipicolinate N-succinyltransferase. The triangular domains are the left-handed parallel beta helices formed by tandem-repeated copies of hexapeptide amino acid sequence motif. Courtesy of Todd W. Beaman, David A. Binder, John S. Blanchard, and Steven L. Roderick, Albert Einstein College of Medicine, Bronx, New York. This book is printed on acid-free paper. Q Copyright 9 1998 by Academic Press All rights reserved. No part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher. Academic Press a division of Harcourt Brace & Company 525 B Street, Suite 1900, San Diego, CA 92101-4495, USA http: / / www.academicpress.com Academic Press 24-28 Oval Road, London NW1 7DX, UK http://www.hbuk.co.uk/ap / Proteins : analysis and design / edited by Ruth Hogue Angeletti. p. cm. Includes bibliographical references and index. ISBN 0-12-058785-8 (hc : alk. p