E-Book Overview
The main idea behind this book is to present a rigorous derivation of the equations that govern light propagation in highly scattering media, with an emphasis on their applications in imaging in biology and medicine. The equations and formulas for diffuse light propagation are derived from the very beginning, and all the necessary analytical expressions needed to complete a complex imaging or characterization problem are presented step by step.
This book provides postgraduate and PhD students with the basic framework and sufficient knowledge in light transport and the related mathematical methods to solve most complex problems that may appear in biomedical applications involving multiple scattered light. All results presented are formal analytical derivations from the complete problem, presenting, in those cases which are relevant, approximations to these expressions.
Readership: Students and professionals working in the field of optical biomedical applications.
E-Book Content
PRINCIPLES OF DIFFUSE LIGHT PROPAGATION
Light Propagation in Tissues with Applications in Biology and Medicine
This page intentionally left blank
PRINCIPLES OF DIFFUSE LIGHT PROPAGATION
Light Propagation in Tissues with Applications in Biology and Medicine
Jorge Ripoll Lorenzo Foundation for Research and Technology - Hellas, Greece
World Scientific NEW JERSEY
•
LONDON
•
SINGAPORE
•
BEIJING
•
SHANGHAI
•
HONG KONG
•
TA I P E I
•
CHENNAI
Published by World Scientific Publishing Co. Pte. Ltd. 5 Toh Tuck Link, Singapore 596224 USA office: 27 Warren Street, Suite 401-402, Hackensack, NJ 07601 UK office: 57 Shelton Street, Covent Garden, London WC2H 9HE
British Library Cataloguing-in-Publication Data A catalogue record for this book is available from the British Library.
PRINCIPLES OF DIFFUSE LIGHT PROPAGATION Light Propagation in Tissues with Applications in Biology and Medicine Copyright © 2012 by World Scientific Publishing Co. Pte. Ltd. All rights reserved. This book, or parts thereof, may not be reproduced in any form or by any means, electronic or mechanical, including photocopying, recording or any information storage and retrieval system now known or to be invented, without written permission from the Publisher.
For photocopying of material in this volume, please pay a copying fee through the Copyright Clearance Center, Inc., 222 Rosewood Drive, Danvers, MA 01923, USA. In this case permission to photocopy is not required from the publisher.
ISBN-13 978-981-4293-76-1 ISBN-10 981-4293-76-8
Printed in Singapore.
Alvin - Principles of Diffuse Light.pmd
1
2/2/2012, 2:10 PM
February 17, 2012
11:57
World Scientific Book - 9in x 6in
To Alicia
v
ws09˙main
This page intentionally left blank
February 17, 2012
11:57
World Scientific Book - 9in x 6in
Foreword
Probing disease with light is the oldest and still most wide-spread clinical examination method world-wide. Every single day at every hospital in the world, doctors will ‘look’ at patients to see discolorations and anatomical changes, they will shine light on them with endoscopes or surgical lamps and they will transilluminate them with pulse oximetry devices to obtain blood saturation measurements or to examine the lung of premature newborns. The familiarity of humans with optical imaging usually hides the fact that a significant part of clinical decision making today is still performed with an ‘optical imaging’ method. It is often believed that whereas a physical examination may be based on a patient visual inspection, more advanced radiologic