Fine Chemicals Through Heterogeneous Catalysis

R. A. Sheldon, H. van Bekkum Fine Chemicals through Heterogeneous Catalysis Other Titles of Interest B. Cornils I W. A. Herrmann Applied Homogeneous Catalysis with Organometallic Compounds 2 Volumes 1996. XXXVI, 1246 pages with 1000 figures and 100 tables. Hardcover. ISBN 3-527-29286-1 Softcover. ISBN 3-527-29594-1 B. Cornils / W. A. Herrmann I R. Schlogl I C.-H. Wong Catalysis from A to Z 2000. XVIII, 640 pages with more than 300 figures and 14 tables. Hardcover. ISBN 3-537-29855-X B. Cornils I W. A. Herrmann Aqueous Phase Organometallic Catalysis 1998. XVI, 631 pages with 180 figures and 76 tables. Hardcover. ISBN 3-527-29478-3 M. Beller I C. Bolm Transition Metals for Organic Synthesis 2 Volumes 1998. LVIII, 1062 pages with 733 figures and 75 tables. Hardcover. ISBN 3-527-29501-1 Roger Arthur Sheldon, Herman van Bekkum Fine Chemicals through Heterogeneous Catalysis OWILEY-VCH Weinheim New York Chichester Brisbane - Singapore Toronto - Prof. Dr. R. A. Sheldon Delft University of Technology Organic Chemistry and Catalysis Julianalaan 136 2628 BL DELFT The Netherlands Prof. Dr. H. van Bekkum Delft University of Technology Organic Chemistry and Catalysis Juhanalaan 136 2628 BL DELFT The Netherlands This book was carefully produced. Nevertheless, authors and publisher do not warrant the information contained therein to be free of errors. Readers are advised to keep in mind that statements, data, illustrations, procedural details or other items may inadvertently be inaccurate. First edition 2001 First reprint, 2002, of the first edition 2001 Library of Congress Card No. applied for British Library Cataloguing-in-Publication Data: A catalogue record for this book is available from the British Library. Die Deutsche Bibliothek - CIP Cataloguing-in-Publication-Data ISBN 3-527-29951-3 0 WILEY-VCH Verlag GmbH. D-69469 Weinheim (Federal Republic of Germany), 2001 Printed on acid-free and chlorine-free paper. All rights reserved (including those of translation in other languages). No part of this book may be reproduced in any form - by photoprinting, microfilm, or any other means - nor transmitted or translated into machine language without written permission from the publishers. Registered names, trademarks, etc. used in this book, even when not specifically marked as such, are not to be considered unprotected by law. Composition: Hagedorn Kommunikation, D-68519 Viernheim. Printing: Strauss Offsetdruck GmbH, D-69503 Morlenbach Bookbinding: Wilhelm Osswald & Co, D-67433 Neustadt Printed in the Federal Republic of Germany. Preface The subject of this book is the application of heterogeneous catalysis in organic synthesis with emphasis on transformations of relevance to fine chemicals manufacture. Both gas and liquid phase reactions are included although the latter are more numerous, analogous to fine chemicals manufacture where substrates and products often have low volatility and/or thermal stability, necessitating operation in the liquid phase. The subject is divided on the basis of the major types of catalytic conversions employed in organic synthesis : acid and base catalysis, hydrogenation and dehydrogenation, oxidation and C-C bond formation. Heterogeneous catalysis has a long history, dating back to the e