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MOLECULAR ENZYMOLOGY, BECAUSE OF ITS CHEMICAL AND MATHEMATICAL content, is often regarded as a formidable and forbidding topic by undergraduates on a biology or biochemistry course, As a result of teaching enzymology to undergraduates for a number of years, we recognize the areas which appear to cause the most common difficulties in conceptual understanding. We feel that a book treating those areas by means of a logical approach carefully developed from basic principles fills a gap in the multiplicity of enzymology texts currently available. In writing this book we h;:lVe had in mind the needs of Honours Biochemistry students, in particular those who may take a special interest in enzymology. The text covers the main bulk of the material required in the second and third years of such courses. In addition, those taking courses in Biological Chemistry may well find the book to be of central interest. The book begins with a description of the fundamentals of catalysis, illustrating these with simple chemical reactions which may be supposed to serve as models of catalytic processes. Protein structure is discussed in terms of the fundamental forces which determine the shape and dynamic behaviour of protein molecules. The approach emphasizes those features thought to be most intimately involved in the catalytic function of enzyme molecules, and is illustrated with specific examples.
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Molecular Enzymology
TERTIARY LEVEL BIOLOGY
A series covering selected areas of biology at advanced undergraduate level. While designed specifically for course options at this level within Universities and Polytechnics, the series will be of great value to specialists and research workers in other fields who require a knowledge of the essentials of a subject.
Titles in the series: Experimentation in Biology Methods in Experimental Biology Visceral Muscle Biological Membranes Comparative Immunobiology Water and Plants Biology of Nematodes An Introduction to Biological Rhythms Biology of Ageing Biology of Reproduction An Introduction to Marine Science Biology of Fresh Waters An Introduction to Developmental Biology Physiology of Parasites Neurosecretion Biology of Communication Population Genetics Structure and Biochemistry of Cell Organelles Developmental Microbiology Genetics of Microbes Biological Functions of Carbohydrates Endocrinology The Estuarine Ecosystem Animal Osmoregulation
Ridgman Ralph Huddart and Hunt Harrison and Lunt Manning and Turner Meidner and Sheriff Croll and Matthews Saunders Lamb Hogarth Meadows and Campbell Maitland Ede Chappell Maddrell and Nordmann Lewis and Gower Gale Reid Peberdy Bainbridge Candy Goldsworthy, Robinson and Mordue McLusky Rankin and Davenport
TERTIARY LEVEL BIOLOGY
Molecular Enzymology CHRISTOPHER
w. WHARTON,
B.Sc., Ph.D.
Lecturer in Biochemistry University of Birmingham and
ROBERT EISENTHAL, A.B., Ph.D. Senior Lecturer in Biochemistry Universityof Bath
Springer Science+ Business Media, LLC
Blackie & Son Limited Bishopbriggs Glasgow G64 2NZ Furnival House 14-18 High Holborn London WC1 V 6BX
© 1981
C. W. Wharton and R. Eisenthal First published 1981
Softcover reprint of the hardcover 1st edition 1981
AIIrights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted, in any form or by any means, electronic, mechanical, recording or otherwise, without prior permission of the Publishers
British Library Cataloguing in Publication Data Wharton, Christopher W. Molecular enzymology.- (Tertiary level biology) 1. Enzymes 1. Title II. Eisenthal, Robert. III. Series 574.19'25 QP601 ISBN 978-1-4615-8534-3 DOI 10.1007/978-1-4615-8532-9
ISBN 978-1-4615-8532-9 (eBook)
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