E-Book Overview
Despite the tremendous progress made during the last few years in understanding the pathogenesis, epidemiology, diagnosis, and treatment of Clostridium difficile-associated intestinal disease, many extremely important and fundamental questions remain to be answered. The objectives of this book are to summarize the available information regarding Clostridium difficile and its role in intestinal disease and to serve as a basis for future investigations in this challenging area. Clostridium difficile: its role in Intestinal Disease. An excellent volume that should appeal not only to the devotee of C difficile but to all gastroenterologists and microbiologists, this will not languish on my library shelves like so many other books I have reviewed. It will be regularly thumbed. --R.H. George, consultant microbiologist, Children's Hospital, Birmingham Clostridium difficile: Its Role in Intestinal disease. The book is well written and informative; it has a vast amount of information packed in it...this book would be a welcome addition to the researchers and clinicians interested in C difficile-associated intestinal diseases. --Edward Balish, University of Wisconsin Medical School
E-Book Content
Clostridium difficile: Its Role in Intestinal Disease Edited by
RIAL D. ROLFE Department of Microbiology Texas Tech University Health Sciences Center School of Medicine Lubbock Texas
SYDNEY M. FINEGOLD Research Service Veterans Administration Wadsworth Medical Center Department of Medicine University of California, Los Angeles School of Medicine Los Angeles, California
ACADEMIC PRESS, INC. Harcourt Brace Jovanovich, Publishers San Diego New York Berkeley Boston London Sydney Tokyo Toronto
COPYRIGHT ©
1988
BY ACADEMIC PRESS, INC.
ALL RIGHTS RESERVED. NO PART OF THIS PUBLICATION MAY BE REPRODUCED OR TRANSMITTED IN ANY FORM OR BY ANY MEANS, ELECTRONIC OR MECHANICAL, INCLUDING PHOTOCOPY, RECORDING, OR ANY INFORMATION STORAGE AND RETRIEVAL SYSTEM, WITHOUT PERMISSION IN WRITING FROM THE PUBLISHER.
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United Kingdom Edition published by ACADEMIC PRESS INC. (LONDON) LTD. 24-28 Oval Road, London NW1 7DX
LIBRARY OF CONGRESS CATALOGING IN PUBLICATION DATA
Clostridium dificile. Includes index. 1. Diarrhea—Microbiology. 2.Clostridium dificile. 3. Colitis—Microbiology. I. Rolfe, Rial D. II. Finegold, Sydney M., Date QR201.D4C55 1988 616.3'40145 87-18828 ISBN 0-12-593410-6 (alk. paper)
PRINTED IN THE UNITED STATES OF AMERICA 88 89 90
9 8 7 6 5 4 3 2 1
Contributors
Numbers in parentheses indicate the pages on which the authors' contributions begin.
Bo Aronsson (99), Department of Infectious Diseases, Karolinska Institute, Roslagstull Hospital, and Department of Bacteriology, National Bacteriological Laboratory, S-114 89 Stockholm, Sweden John Bartlett (1), Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205 S. P. Borriello (65), Division of Communicable Diseases, Clinical Research Centre, Harrow, Middlesex HAI 3UJ, England R. J. Carman (65), Department of Anaerobic Microbiology, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061 Michael Cooperstock (45), Section of Infectious Disease, Department of Child Health, University of Missouri School of Medicine, Columbia, Missouri 65212 Sam T. Donta (169), Medical Service, Newington Veterans Administration Medical Center and Infectious Disease Service, University of Connecticut Health Center, Farmington, Connecticut 06111 Martha A. C. Edelstein (287), Clinical Anaerobic Bacteriology Research Laboratory, Infectious Disease Section, Veterans Administration Wadsworth Medical Center, Los Angeles, California 90073 Robert Fekety (127), Divisio