Comprehensive Coordination Chemistry Ii. Bio-coordination Chemistry

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Comprehensive Coordination Chemistry II (CCC II) is the sequel to what has become a classic in the field, Comprehensive Coordination Chemistry, published in 1987. CCC II builds on the first and surveys new developments authoritatively in over 200 newly comissioned chapters, with an emphasis on current trends in biology, materials science and other areas of contemporary scientific interest.

E-Book Content

Introduction to Volume 8 Since the publication of CCC (1987), bioinorganic chemistry has blossomed and matured as an interdisciplinary field, which is surveyed in this volume from the perspective of coordination chemistry. Fully comprehensive coverage of biological inorganic chemistry is not possible, so a subset of topics is presented that captures the excitement of the field and reflects the scope and diversity of the systems and research approaches used. As an introduction, a summary of structural motifs that pervade bioinorganic systems is presented (Chapter 1). Subsequent chapters focus on the nature of the metal sites in proteins that participate in electron transfer (Chapters 2–4) and on the transport and storage of metal ions within the biological milieu (Chapters 5–9). The diverse and biologically important array of metalloproteins that bind and activate dioxygen and perform oxidation reactions are then discussed (Chapters 10–18). To complete the presentation of metal–dioxygen chemistry, superoxide processing systems and photosynthetic oxygen evolution are portrayed (Chapters 19–20). The following sections focus on the activation of other small molecules (H2, Chapter 21; N2, Chapter 22), mono- and dinuclear metal sites that perform hydrolysis reactions (Chapters 23–24), and the burgeoning bio-organometallic area (Chapter 25). Proteins with synergistic metal–radical sites are discussed in Chapter 26. Iron–sulfur clusters are revisited in Chapter 27, which presents t
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