This book looks at the mathematical foundations of the models which is crucial for correct interpretation of the outputs of the models. A bioinformatician should be able not only use software packages, but also know the mathematics behind these packages. From this point of view, mathematics departments throughout the world have a major role to play in bioinformatics education by teaching courses on the mathematical foundations of bioinformatics. The author wrote this book based on his lecture notes for his courses. It combines several topics in biological sequence analysis with mathematical and statistical material required for such analysis.
Alexander Isaev
Introduction to Mathematical Methods in Bioinformatics With 76 Figures and 3 Tables
Alexander Isaev Australian National University Department of Mathematics Canberra, ACT 0200 Australia e-mail:
[email protected]
Corrected Second Printing 2006
Mathematics Subject Classification (2000): 91-01 (Primary) 91D20 (Secondary)
Library of Congress Control Number: 2006930998
ISBN: 3-540-21973-0 ISBN: 9783540219736 This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilm or in any other way, and storage in data banks. Duplication of this publication or parts thereof is permitted only under the provisions of the German Copyright Law of September 9, 1965, in its current version, and permission for use must always be obtained from Springer. Violations are liable for prosecution under the German Copyright Law. Springer is a part of S