Insulin Resistance: The Metabolic Syndrome X (contemporary Endocrinology)


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CONTEMPORARY ENDOCRINOLOGY ™ Insulin Resistance The Metabolic Syndrome X Edited by Gerald M. Reaven, MD Ami Laws, MD HUMANA PRESS Contents i INSULIN RESISTANCE THE METABOLIC SYNDROME X ii Contents CONTEMPORARY ENDOCRINOLOGY P. Michael Conn, SERIES EDITOR 19. Human Growth Hormone: Basic and Clinical Research, edited by ROY G. SMITH AND MICHAEL O. THORNER, 1999 18. Menopause: Endocrinology and Management, edited by DAVID B. SEIFER AND ELIZABETH A. KENNARD, 1999 17. The IGF System: Molecular Biology, Physiology, and Clinical Applications, edited by RON G. ROSENFELD AND CHARLES T. ROBERTS, JR. 1999 16. Neurosteroids: A New Regulatory Function in the Nervous System, edited by ETIENNE-EMILE BAULIEU, MICHAEL SCHUMACHER, AND PAUL ROBEL, 1999 15. Autoimmune Endocrinopathies, edited by ROBERT VOLPÉ, 1999 14. Hormone Resistance Syndromes, edited by J. LARRY JAMESON, 1999 13. Hormone Replacement Therapy, edited by A. WAYNE MEIKLE, 1999 12. Insulin Resistance: The Metabolic Syndrome X, edited by GERALD M. REAVEN AND AMI LAWS, 1999 11. Endocrinology of Breast Cancer, edited by ANDREA MANNI, 1999 10. Molecular and Cellular Pediatric Endocrinology, edited by STUART HANDWERGER, 1999 9. The Endocrinology of Pregnancy, edited by FULLER W. BAZER, 1998 8. Gastrointestinal Endocrinology, edited by GEORGE H. GREELEY, JR., 1999 7. Clinical Management of Diabetic Neuropathy, edited by ARISTIDIS VEVES, 1998 6. G Proteins, Receptors, and Disease, edited by ALLEN M. SPIEGEL, 1998 5. Natriuretic Peptides in Health and Disease, edited by WILLIS K. SAMSON AND ELLIS R. LEVIN, 1997 4. Endocrinology of Critical Diseases, edited by K. PATRICK OBER, 1997 3. Diseases of the Pituitary: Diagnosis and Treatment, edited by MARGARET E. WIERMAN, 1997 2. Diseases of the Thyroid, edited by LEWIS E. BRAVERMAN, 1997 1. Endocrinology of the Vasculature, edited by JAMES R. SOWERS, 1996 Contents iii INSULIN RESISTANCE THE METABOLIC SYNDROME X Edited by GERALD M. REAVEN Shaman Pharmaceuticals, Inc., South San Francisco, CA and Stanford University School of Medicine, Stanford, CA AMI LAWS Stanford University School of Medicine, Stanford, CA HUMANA PRESS, TOTOWA, NEW JERSEY © 1999 Humana Press Inc. iv 999 Riverview Drive, Suite 208 Totowa, New Jersey 07512 Contents For additional copies, pricing for bulk purchases, and/or information about other Humana titles, contact Humana at the above address or at any of the following numbers: Tel: 201-256-1699; Fax: 201-256-8341; E-mail: [email protected] or visit our website at http://humanapress.com All rights reserved. No part of this book may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying, microfilming, recording, or otherwise without written permission from the Publisher. All articles, comments, opinions, conclusions, or recommendations are those of the author(s), and do not necessarily reflect the views of the publisher. This publication is printed on acid-free paper. ∞ ANSI Z39.48-1984 (American National Standards Institute) Permanence of Paper for Printed Library Materials. Photocopy Authorization Policy: Authorization to photocopy items for internal or personal use, or the internal or personal use of specific clients, is granted by Humana Press Inc., provided that the base fee of US $10.00 per copy, plus US $00.25 per page, is paid directly to the Copyright Clearance Center at 222 Rosewood Drive, Danvers, MA 01923. For those organizations that have been granted a photocopy license from the CCC, a separate system of payment has been arranged and is acceptable to Humana Press Inc. The
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