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The latest guidance on challenging and controversial aspects of colorectal cancerColorectal cancer is one of the most common forms of cancer in the US and Europe. Thousands of people are diagnosed with the disease every year and nearly half of these die as a result. As colorectal cancer is curable when detected early, a significant proportion of these deaths could be prevented by earlier diagnosis.Much has changed since the publication of the first edition of this book in 2001: introduction of screening programs, improved diagnosis and surgery for rectal cancer, and advances in adjuvant and palliative medical therapy to name but a few.Challenges in Colorectal Cancer provides the most up-to-date information on the new and emerging treatments. The second edition looks at the total patient management of this condition and is aimed at the entire medical team caring for those with colorectal cancer. It also contains the latest guidelines on epidemiology and prevention of colorectal cancer, and the application of molecular genetics.The expanded international editor team present advice on surgical management, including new laparoscopic and endoscopic techniques and the role of the pathologist. They also review hot topics in colorectal cancer treatment, including the role of radiotherapy, options for chemotherapy and new developments in vaccines and immunotherapy.
E-Book Content
CHALLENGES IN
Colorectal Cancer
C H A L L E NG E S I N .......................................................................................................................
Colorectal Cancer
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EDITED BY
John H. Scholefield
Axel Grothey
Professor of Surgery University Hospital Nottingham, UK
Professor Division of Medical Oncology Mayo Clinic Rochester, Minnesota, USA
Herand Abcarian
Tim Maughan
Turi Josefsen Professor and Chairman Department of Surgery University of Illinois College of Medicine Chicago, Illinois, USA
Professor of Cancer Studies University of Cardiff Cardiff, UK
SECOND EDIT IO N
© 2000 by Blackwell Science Ltd © 2006 by Blackwell Publishing Ltd Blackwell Publishing, Inc., 350 Main Street, Malden, Massachusetts 02148-5020, USA Blackwell Publishing Ltd, 9600 Garsington Road, Oxford OX4 2DQ, UK Blackwell Publishing Asia Pty Ltd, 550 Swanston Street, Carlton, Victoria 3053, Australia The right of the Author to be identified as the Author of this Work has been asserted in accordance with the Copyright, Designs and Patents Act 1988. All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted, in any form or by any means, electronic, mechanical, photocopying, recording or otherwise, except as permitted by the UK Copyright, Designs and Patents Act 1988, without the prior permission of the publisher. First published 2000 Second edition 2006 1
2006
Library of Congress Cataloging-in-publication Data Challenges in colorectal cancer/edited by John H. Schofield. . .[et al.]. – 2nd ed. p. ; cm. Includes index. ISBN-13: 978-1-4051-2706-6 (alk. paper) ISBN-10: 1-4051-2706-6 (alk. paper) 1. Colon (Anatomy)—Cancer. 2. Rectum—Cancer. I. Scholefield, John H. [DNLM: 1. Colorectal neoplasms—therpay. 2. Colorectal Surgery. WI 529 C437 2006] RC280.C6C47 2006 616.99 4347—dc22 2006000979 ISBN-13: 978-1-4051-2706-6 ISBN-10: 1-4051-2706-6 A catalogue record for this title is available from the British Library Set in 10/13.5 Sabon by Newgen Imaging Systems (P) Ltd., Chennai, India Printed and bound in India by Replika Press PVT Ltd Commissioning Editor: Alison Brown Editorial Assistant: Jennifer Seward Development Editor: Elisabeth Dodds Production Controller: