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This book discusses the most important techniques available for longitudinal data analysis, from simple techniques such as the paired t-test and summary statistics, to more sophisticated ones such as generalized estimating of equations and mixed model analysis. A distinction is made between longitudinal analysis with continuous, dichotomous and categorical outcome variables. The emphasis of the discussion lies in the interpretation and comparison of the results of the different techniques. The second edition includes new chapters on the role of the time variable and presents new features of longitudinal data analysis. Explanations have been clarified where necessary and several chapters have been completely rewritten. The analysis of data from experimental studies and the problem of missing data in longitudinal studies are discussed. Finally, an extensive overview and comparison of different software packages is provided. This practical guide is essential for non-statisticians and researchers working with longitudinal data from epidemiological and clinical studies.
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more information - www.cambridge.org/9781107030039 Applied Longitudinal Data Analysis for Epidemiology A Practical Guide Applied Longitudinal Data Analysis for Epidemiology A Practical Guide Second Edition Jos W. R. Twisk Department of Epidemiology and Biostatistics Medical Center and Department of Health Sciences, Vrije Universteit Amsterdam, the Netherlands cambridge university press Cambridge, New York, Melbourne, Madrid, Cape Town, Singapore, S˜ao Paulo, Delhi, Mexico City Cambridge University Press The Edinburgh Building, Cambridge CB2 8RU, UK Published in the United States of America by Cambridge University Press, New York www.cambridge.org Information on this title: www.cambridge.org/9781107699922 C Jos W. R. Twisk 2003 First edition C Jos W. R. Twisk 2013 Second edition This publication is in copyright. Subject to statutory exception and to the provisions of relevant collective licensing agreements, no reproduction of any part may take place without the written permission of Cambridge University Press. First edition first published 2003 Second edition first published 2013 Printed and bound in the United Kingdom by the MPG Books Group A catalogue record for this publication is available from the British Library Library of Congress Cataloguing in Publication data Twisk, Jos W. R., 1962– Applied longitudinal data analysis for epidemiology : a practical guide / Jos W. R. Twisk, Department of Epidemiology and Biostatistics, Medical Centre and the Department of Health Sciences of the Vrije Universteit, Amsterdam. – Second edition. pages cm Includes bibliographical references and index. ISBN 978-1-107-03003-9 (hardback) – ISBN 978-1-107-69992-2 (paperback) 1. Epidemiology – Research – Statistical methods. 2. Epidemiology – Longitudinal studies. 3. Epidemiology – Statistical methods. I. Title. RA652.2.M3T95 2013 614.4 – dc23 2012050470 ISBN 978-1-107-03003-9 Hardback ISBN 978-1-107-69992-2 Paperback Cambridge University Press has no responsibility for the persistence or accuracy of URLs for external or third-party internet websites referred to in this publication, and does not guarantee that any content on such websites is, or will remain, accurate or appropriate. Every effort has been made in preparing this book to provide accurate and up-to-date information which is in accord with accepted standards and practice at the time of publication. Although case histories are drawn from actual cases, every effort has been made to disguise the identities of the individuals involved. Nevertheless, the authors, editors and publishers can make no warranties that the information contained herein is totally free from error, not least because clinical standards are constantly changing through research and regulation. The