E-Book Overview
Macromolecules in solutions can be distinctly characterised by their transport behaviour in solution phase. The study of the transport processes includes diffusion coefficient, sedimentation coefficient, intrinsic viscosity and friction constant. The question arises as to how to explicitly characterise the macromolecules from the data of coefficients. This book answers this question in a systematic manner. It provides physical interpretation of the data obtained in macromolecular transport phenomena in a given system and also addresses some important issues and concepts related to biopolymers such as proteins and nucleic acids. The application of concepts like conformational properties and salient physicochemical features of protein and nucleic acids is also elucidated in the book. Based on the molecular structure, it provides the essential concepts which can be used to model and analyse the static and transport behaviour of polymers and biopolymers.
E-Book Content
Fundamentals of Polymer Physics and Molecular Biophysics Himadri B. Bohidar Jawaharlal Nehru University Cambridge House, 4381/4 Ansari Road, Daryaganj, Delhi 110002, India Cambridge University Press is part of the University of Cambridge. It furthers the University’s mission by disseminating knowledge in the pursuit of education, learning and research at the highest international levels of excellence. www.cambridge.org Information on this title: www.cambridge.org/9781107058705 © Himadri B. Bohidar 2015 This publication is in copyright. Subject to statutory exception and to the provisions of relevant collective licensing agreements, no reproduction of any part may take place without the written permission of Cambridge University Press. First published 2015 Printed in India A catalogue record for this publication is available from the British Library Library of Congress Cataloging-in-Publication Data Bohidar, Himadri B. Fundamentals of polymer physics and molecular biophysics / Himadri B. Bohidar. pages cm Includes bibliographical references and index. Summary: “Provides a physical interpretation of the data obtained in macromolecular transport phenomena in a given system and also addresses some important issues and concepts related to biopolymers such as proteins and nucleic acids”-- Provided by publisher. ISBN 978-1-107-05870-5 (hardback) 1. Polymers. 2. Physics. 3. Biophysics. I. Title. QD281.P6B62 2014 530.4’13--dc23 2014007362 ISBN 978-1-107-05870-5 Hardback Cambridge University Press has no responsibility for the persistence or accuracy of URLs for external or third-party internet websites referred to in this publication, and does not guarantee that any content on such websites is, or will remain, accurate or appropriate. Contents List of Figures List of Tables Preface xi xvii xix 1. Essential Thermodynamic and Statistical Concepts 1.1. Irreversible thermodynamics 1.2. Postulates in irreversible thermodynamics 1.3. Phenomenological forces and fluxes 1.4. Gibbs–Duhem equation 1.5. Statistical parameters 1.6. Probability distributions 1.6.1. Binomial distribution 1.6.2. Gaussian distribution 1.6.3. Poisson distribution 1.6.4. Multi-variable distributions Bibliography Exercises 1 4 4 5 8 9 10 12 13 15 17 17 2. Polymer Structure and Nomenclature 2.1. Basic structures 2.2. Some common polymers 2.3. Molecular weight and polydispersity 2.4. Forces and interactions 2.4.1. Covalent bond 2.4.2. Ionic bond 2.4.3. Coulomb forces 2.4.4. Charge–dipole force 2.4.5. Lennard–Jones potential 2.4.6. Hydrogen bond 2.5. Polymer gels and networks Summary References Exercises 18 21 27 31 31 31 31 31 32 32 33 37 37 38 iv╇ |╇ Contents 3. Polymer Solutions 3.1. Basic concepts 3.2. Ideal solution model 3.3. Real polymer solutions 3.4. Flory–Huggins model 3.5. Change i