Functional magnetic resonance imaging (fMRI) and electroencephalography (EEG) are very important and complementary modalities since fMRI offers high spatial resolution while EEG provides a direct measurement of neuronal activity with high temporal resolution. Interest in the integration of these two types of data is growing rapidly as it promises to yield important new insights into human brain activity, as has already occurred in the case of epilepsy. Indeed, it seems certain that integrated EEG-fMRI will play an increasing role in neuroscience and in the clinical study of various brain disorders. This book discusses in depth all aspects of EEG-fMRI, including physiological principles and technical and methodological issues such as EEG<STRONG>artefact reduction methods, image quality, and data analysis strategies. Detailed consideration is given to all potential applications, primarily in the fields of sleep research, cognitive neuroscience, and clinical neurology and psychiatry. All of the authors are recognized experts in the field, and the text is supported by numerous informative illustrations.
EEG–fMRI Christoph Mulert • Louis Lemieux (Eds.) EEG–fMRI Physiological Basis, Technique and Applications PD Dr. Christoph Mulert Universitätsklinikum München Psychiatrische Klinik Ludwig-MaximiliansUniversität München (LMU) Nußbaumstr. 7 80336 München Germany
[email protected] ISBN: 978-3-540-87918-3 Louis Lemieux, PhD UCL Institute of Neurology Department of Clinical and Experimental Epilepsy University College London Queen Square London United Kingdom WC1N 3BG
[email protected] e-ISBN: 978-3-540-87919-0 DOI: 10.1007/978-3-540-87919-0 Springer Heidelberg Dordrecht London New York Library of Congress Control Number: 2009926259 © Springer-Verlag Berlin Heidelberg 2010 This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilm or in any other way, and storage in data banks. Duplication of this publication or parts thereof is permitted only under the provisions of the German Copyright Law of September 9, 1965, in its current version, and permission for use must always be obtained from Springer. Violations are liable to prosecution under the German Copyright Law. The use of general descriptive names, registered names, trademarks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. Product liability: The publishers cannot guarantee the accuracy of any information about dosage and application contained in this book. In every individual case the user must check such information by consulting the relevant literature. Cover design: eStudioCalamar Figueres/Berlin Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com) Foreword It is a great pleasure to write a preface for this book, which I see as the first comprehensive treatment of human brain mapping using multimodal approaches. The content and ambitions addressed in these pages represent some of the most challenging and advanced applications in imaging neuroscience. Since the inception of modern brain mapping two decades ago, there has been an implicit hope that different measurements of brain activity might be